Tülin U. Morçöl, PhD

President and Chief Scientific Officer

Dr. Morçöl founded CaPtivate Pharmaceuticals as a spin-off from BioSante Pharmaceuticals in 2011.  Prior to CaPtivate, she worked at BioSante for 13 years, first as Associate Director of R&D and then Director of Preclinical Development.  During her work at BioSante, she focused on exploring novel formulation strategies for delivery of therapeutic drugs and vaccines for needle-free administration, and developing processes for large scale manufacturing of CaP nanoparticles. She expanded the applications of CaP-based technologies to selectively isolating recombinant proteins from the milk of transgenic livestock and developing formulations for esthetic medicine. In 2006 she led the relocation of BioSante’s R&D facilities from Atlanta, GA, to Pennsylvania Biotechnology Center in Doylestown, PA and established BioSante-PA. Prior to working in pharmaceutical industry, she worked at the Morehouse School of Medicine (MSM), Department of Neurosciences, Atlanta, GA. Before moving to the USA, Dr. Morçöl worked as research scientist for the Turkish Atomic Energy Agency for 5 years, during which she was awarded a research scholarship at Hoffman-La Roche, Basel, Switzerland by the International Atomic Energy Agency. She received her BS and MS degrees in Chemical Engineering at Middle East Technical University and Ankara University in Turkey.  She earned her PhD in Biochemical Engineering from Virginia Polytechnic Institute and State University in 1992. At Virginia Tech, she studied bioprocess engineering-process development for large-scale manufacture of transgenically produced recombinant proteins, under the mentorship of Dr. William H. Velander and as a member of Transgenic Animal Research Team. The team’s most pioneering achievement was the generation of the world’s first transgenic livestock, the female pig known as Genie, expressing human plasma protein C in her milk. She received a Research Excellence Award from Virginia Tech for her doctoral research in 2002.  Dr. Morçöl is also serving as the Vice President of Business Development at ImmProNano Solutions, a small R&D contract research company providing immunology, proteomics, and nano-formulation services for vaccine and drug compounds. She is the inventor or co-inventor in all patents and patent applications related to CaP nanoparticle technology. 

Scientific Advisory Team

Banu Onaral, PhD

H. H. Sun Professor Biomedical Engineering and Electrical Engineering, Senior Advisor to the President, Global Partnerships, Drexel University, Philadelphia, PA.

 

Dr. Onaral is H. H. Sun Professor of Biomedical Engineering and Electrical Engineering at Drexel University, Philadelphia, PA. She holds a PhD [1978] in Biomedical Engineering from the University of Pennsylvania and BSEE [1973] and MSEE [1974] in Electrical Engineering from Bogazici University, Istanbul, Turkey. Dr. Onaral joined the faculty of the Department of Electrical and Computer Engineering and the Biomedical Engineering and Science Institute in 1981. Since 1997, she has served as the founding Director of the School of Biomedical Engineering Science and Health Systems. She has led major research and development projects sponsored by the National Science Foundation (NSF), National Institutes of Health (NIH), Office of Naval Research (ONR), DARPA and Department of Homeland Security (DHS). Dr. Onaral's translational research efforts for rapid commercialization of biomedical technologies developed at Drexel and its partner institutions have resulted in the creation of the Translational Research in Biomedical Technologies program. This initiative brings together academic technology developers with entrepreneurs, regional economic development agencies, as well as local legal, business, and investment communities. Under her leadership, the Coulter Translational Research Partnership Award recognized the program following a highly competitive selection process among 63 institutions in North America. At the end of an initial five-year term, universities successful in institutionalizing translational research will receive an endowment to ensure the perpetuity of the program. Her professional responsibilities have included service on the Editorial Board of journals and the CRC Biomedical Engineering Handbook as Section Editor for Biomedical Signal Analysis. She served as President of the IEEE Engineering in Medicine and Biology Society (EMBS), the largest member-based biomedical engineering society in the world. She currently serves as the President of the Turkish American Scientists and Scholars Association (TASSA).

Anthony Hickey, PhD, DSc

Distinguished Fellow, Aerosol and Nanomaterials Engineering

Founder and President, Cirrus Pharmaceuticals, Inc., RTP, NC

Research Pharmacologist, RTI Internationals, RTP, NC

Emeritus Professor, University of North Carolina, School of Medicine and Eshelman School of Pharmacy, Chapel Hill, NC

 

Dr. Hickey is Distinguished RTI Fellow, at the Research Triangle Institute, Emeritus Professor of Molecular Pharmaceutics of the Eshelman School of Pharmacy (2010-present, Professor 1993-2010), and Adjunct Professor  of Biomedical Engineering in the School of Medicine, at the University of North Carolina at Chapel Hill. He obtained Ph.D. (1984) and D.Sc. (2003) degrees in pharmaceutical sciences from Aston University, Birmingham, UK. Following postdoctoral positions, at the University of Kentucky (1984-1988) Dr. Hickey joined the faculty at the University of Illinois at Chicago (1988-1993). He is a Fellow of the Royal Society of Biology (2000), the American Association of Pharmaceutical Scientists (2003) and the American Association for the Advancement of Science (2005). He received the Research Achievement Award of the Particulate Presentations and Design Division of the Powder Technology Society of Japan (2012), the Distinguished Scientist Award of the American Association of Indian Pharmaceutical Scientists (2013) and the David JW Grant Award in Physical Pharmacy of the American Association of Pharmaceutical Scientists (2015). He has published numerous papers and chapters in the pharmaceutical and biomedical literature, one of which received the AAPS Meritorious Manuscript Award in 2001. He has edited five texts on pharmaceutical inhalation aerosols and co-authored three others on ‘Pharmaceutical Process Engineering’, pharmaceutical particulate science and ‘Pharmaco-complexity’. He is founder (1997, and formerly President and CEO, 1997-2013) of Cirrus Pharmaceuticals, Inc., which was acquired by Kemwell Pharma in 2013; founder (2001, and formerly CSO, 2002-2007) of Oriel Therapeutics, Inc, which was acquired by Sandoz in 2010 and founder and CEO of Astartein, Inc. (2013-present); member of the Pharmaceutical Dosage Forms Expert Committee of the United States Pharmacopeia (USP, 2010–2015, Chair of the sub-committee on Aerosols) and formerly Chair of the Aerosols Expert Committee of the USP (2005-2010). He is Principal Investigator for the ‘NIH Nanomaterial Registry’ (a multi-institute program). Dr. Hickey conducts a multidisciplinary research program in the field of pulmonary drug and vaccine delivery for treatment and prevention of a variety of diseases. Dr. Hickey holds 17 patents and has authored numerous books, book chapters, and more than 160 journal articles.

Timothy M. Block, PhD

President and Director, Hepatitis B Foundation and Pennsylvania Biotechnology Center of Bucks, Doylestown, PA

President and Director, Baruch S. Blumberg Institute, Doylestown, PA

Professor, Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA


Dr. Timothy Block is the Co-Founder and volunteer President of the Hepatitis B Foundation and its research affiliate the Institute for Hepatitis and Virus Research. He has been involved in viral hepatitis research for more than 25 years and is internationally recognized for his outstanding scholarship and scientific contributions. Dr. Block is a Professor of Microbiology and Immunology, Drexel University College of Medicine, and Director of the Drexel Institute for Biotechnology and Virology Research. Dr. Block received his Ph.D. from SUNY - Buffalo: Roswell Park Memorial Institute, Buffalo, NY and completed his post-doctoral training at Princeton University, Princeton, NJ.  He later studied at the University of Oxford, Oxford, England as a Sabbatical Fellow. He received an honorary M.D. in 1999, when he was elected to the Bulgarian National Academy. At Oxford University, working with Dr. Baruch S. Blumberg (Nobel Laureate) and Prof. Raymond Dwek (Fellow, Royal Society), he discovered a plant sugar that has now received the trade name “glycovir”, which is in preclinical studies. It may open the door to a new family of anti-hepatitis B agents and provide a valuable tool in the fight against hepatitis B.  Dr. Block continues to study chronic viral diseases, including the management and early detection of hepatitis B/C and the molecular pathogenesis of herpesviruses infection. 

Ramila Philip, PhD

Co-founder, President and Chief Scientific Officer, Chairman of the board of directors at Immunotope Inc., Doylestown, PA

Co-founder, ImmProNano Solutions LLC, Doylestown, PA

 

Dr. Philip is the co-founder of ImmProNano.  Dr. Philip is also the co-founder, President and Chief Scientific Officer and chairman of the board of directors at Immunotope Inc.  She also holds adjunct professor positions at the Drexel University, Department of Microbiology and Immunology and Blumberg Institute, a non-profit research institute of Hepatitis B Foundation.  Dr. Philip developed immunoproteomics platform technologies and immunotherapy target discovery strategies at Immunotope.  Her work included antigen discovery for ovarian, breast, prostate, lung and colon cancers and in infectious disease including HBV, HCV and Dengue viruses.  Her discoveries lead to Phase I clinical trials in ovarian and breast cancer patients at Duke University.  Prior to Immunotope, Dr. Philip was head of Research, Product and Business Development at Argonex Pharmaceuticals, (current Millipore) and Vice President of Product Development and Scientific Affairs at Upstate Inc.  Prior to Upstate, Dr. Philip was the Senior Director of Oncology and Gene Therapy at Rhone Poulenc Rorer Gencell (current Sanofi).  Dr. Philip developed several immunotherapy and gene therapy products from research to early phase clinical testing at RPR Gencell, including Phases I-III for a renal cancer cell therapy product, a Phase I gene therapy vaccine for breast cancer and a Phase I melanoma vaccine.  Prior to joining RPR Gencell, Dr. Philip was an Assistant Research Immunologist at UCSF and worked at the Cancer Research Institute for 8 years.  Dr. Philip earned her Ph.D. in Immunology in India and did her postdoctoral training at the Institute of Immunology, Basel, Switzerland.  Dr. Philip has over 20 years of experience in the biotech industry and has developed several biotherapeutic products.  She has over 85 publications in major scientific journals such as Nature and Journal of Experimental Medicine and over 10 patents.  She was one of the top 50 business women in Pennsylvania awardees in 2008.